Isabel Hofmeyr : The Portable Bunyan

Late Pleistocene human skull from Hofmeyr, South Africa, and modern human origins.

The lack of Late Pleistocene human fossils from sub-Saharan Africa has limited paleontological testing of competing models of recent human evolution. We have dated a skull from Hofmeyr, South Africa, to 36.2 +/- 3.3 thousand years ago through a combination of optically stimulated luminescence and uranium-series dating methods. The skull is morphologically modern overall but displays some archai...

Point Mutation Analysis of PMP22 in Patients Referred for Hereditary Neuropathy with Liability to Pressure Palsies

A cohort of 404 patients referred for hereditary neuropathy with liability to pressure palsies was tested initially for the common PMP22 whole gene deletion. 94 whole gene deletions were detected, plus three partial gene deletions, and the remaining 307 patients were screened for PMP22 point mutations. Nine point mutations were identified (8.5% of all mutations), eight of which were in exon 5, ...

The ironic effects of weight stigma

Effects of vitamin E deficiency on total polyunsaturated fatty acids in rats and chicks.

The hypothesis that vitamin E acts mainly as a physiological antioxidant suggests that, in its absence, loss of many types of oxidizable substances may occur. Considerable importance has been attached, in this connexion, to the polyunsaturated fatty acids (PUFA), because of their chemical structure and because of their biochemical role in structural elements of the cell. Pritchard & Singh (1960...

Engineering an Immune System1